Famine versus feast: understanding the metabolism of tumors in vivo
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Oxidants, such as superoxide anion (O 2 ) and hydrogen peroxide (H 2 O 2 ), are produced by exogenous factors (i.e., drugs, infection) and also are formed within red cells as a consequence of reactions of hemoglobin with oxygen
It may help reduce body fat, shrink fat cells, increase energy, improve mitochondrial function, preserve muscle during weight loss, enhance insulin sensitivity, and support overall metabolic health
Notably, gut microbiota metabolites suppress intestinal epithelial Hypoxia-inducible factor-2 alpha (HIF-2) activity and reduce the expression of FTN and, thus, regulate the host iron absorption pathway (Mao et al., 2024)
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