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Antioxidant Approach for the Treatment of Ischemia/Reperfusion Injury Considering the relevant part played by oxidative stress in hepatic I/R injury, many attempts have been made to counteract this impaired condition

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Although additional studies are required to clarify the molecular mechanisms responsible for hyperhomocysteinemia-induced vascular disorders, there is evidence that the direct cytotoxicity of markedly elevated homocysteine and/or of its oxidized by-products (homocysteine thiolactone, homocysteine sulfinic acid, and homocysteic acid) damages endothelial cells (Dudman et al, 1991

Tidsskrift for den Norske Laegeforening: Tidsskrift for Praktisk Medicin, ny Raekke 2006;126:23702

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The one we always blame for melasmamore on that later)