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Similarly, primary cultures of embryonic rat-derived NSPCs respond to E2 increasing their proliferation ( GPER-1 has been found to be widely expressed in NSPCs (Zhang et al., 2019

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Dose at 5mg/kg orally once daily for 8 weeks, then assess synaptic density, PSD-95 expression, and spatial memory performance 24 weeks post-treatment to capture durability

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Protein antioxidant response to the stress and the relationship between molecular structure and antioxidant function