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the FDA rejected its NDI petition as a dietary supplement in 2014

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Vitamin C in its ascorbic acid form is a notable example

It was previously available through compounding pharmacies as a bulk drug substance, but the FDA reclassified it as a Category 2 substance, which effectively restricts compounding pharmacies from producing it

Elevated vitamin B12 (cobalamin) levels in the blood are often discovered incidentally during routine blood tests, as high B12 itself rarely causes direct symptoms

Hydroxocobalamin plays a crucial role in the treatment of cyanide poisoning, which can occur due to smoke inhalation or ingestion of certain chemicals