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Markel U, Essani KD, Besirlioglu V, Schiffels J, Streit WR, Schwaneberg U (2020) Advances in ultrahigh-throughput screening for directed enzyme evolution

Storage shortcuts room temperature storage, repeated freeze-thaw cycles of reconstituted solution, extended use past 28-day reconstituted shelf life introduce variables that compromise research integrity

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18 CuiL.ZhouH.ZhaoH.ZhouY.XuR.XuX.et al (2012)

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In fact, there is not even a single clinical trial or any published evidence that evaluates its efficacy & safety as a skin-whitening agent