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Androgens have been shown to downregulate the expression of bile-salt export pump (BSEP) and multidrug resistanceassociated proteins (MRPs), resulting in bile-acid retention and cytotoxic accumulation within hepatocytes

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It appears to reset the underlying system, not just mask the symptom, and no dependence or withdrawal has been documented

As we age, or when we face high levels of stress and poor nutrition, our natural levels of this molecule can begin to dip

These molecular defects may help explain the neurodevelopmental delays characteristic of ZSD and highlight how zinc status modulates lipid catabolism and redox homeostasis

A qualified healthcare professional can evaluate your symptoms and determine whether any underlying issues need addressing