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Dihexa reversed cognitive deficits induced by scopolamine (an anticholinergic agent) in rodent models, suggesting relevance to cholinergic aspects of cognitive impairment
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All experiments were conducted in a buffer solution containing 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM dithiothreitol (DTT), and 5% dimethyl sulfoxide (DMSO)
