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In phase 2 trials, cagrilintide alone produced dose-dependent reductions in body weight, with participants on the highest dose (4.5 mg weekly) losing roughly 10-15% of body weight over 26 weeks

Discontinue use if irritation, redness, or rash occurs

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Irritation impairs the barrier function of already-thin skin, worsening photoaging over time

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Thomas T, Stefanoni D, Dzieciatkowska M, Issaian A, Nemkov T, Hill RC, et al