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This greater effectiveness of Nano-Lut needs to be further elucidated, however, it might be attributed to its ability to cross the BBB more easily than Nano-Bc and its stability in addition to Lut and Nano-Lut proved in vitro antioxidant potency more than Bc and Nano-Bc in our previous work 48

RA is characterized by chronic inflammation of the synovial joints, leading to joint damage and deformity

The timeline for noticeable improvements can vary depending on factors such as wound severity, overall health, and treatment consistency