Noradrenergic hyperactivity has been shown to be an important component of the stress response and dysregulation of noradrenergic signaling has been implicated in the pathogenesis of anxiety and depression disorders
-synuclein could induce generation of abundant ROS and inflammatory factors, causing lipid peroxidation and death of neurons [177]
Ethics declarations Competing interests The author is employed by, and has financial holdings in, Telik, Inc
Ishihara M, Matsunaga S, Islam R, Shibata O, Chung UI (2024) A policy overview of Japans progress on dementia care in a superaged society and future challenges
This oxidative damage results to modifications of DNA, proteins, and lipids, culminating in the formation of various oxidation products
In blood, GSH levels generally decline with age across studies