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PMC 6450803

[Abstract]2021 Nov 26:28:101177

Hand 18 , 407412 (2023)

J Huntingtons Dis

The binding of a single GSH molecule locks together two adjacent VP1 subunits within a pentamer and in the process confers order on the C-terminus of the VP3 subunit, providing a mechanism of stabilisation by GSH during capsid morphogenesis and the formation of pentameric assemblies

Recently, it was shown that ALL subtypes are associated with differential accumulation of MTX-PG levels: ALL harboring TCF3-PBX1 or ETV6-RUNX1 fusions presented lower MTX-PG levels, whereas hyperdiploid and BCR-ABL-like ALL had higher MTX-PG levels than other subtypes (10)