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In contrast, inhibition of autophagy by intravitreal injection of 3-methyladenine, a potent inhibitor of autophagosome maturation, was neuroprotective in ischemia and chronic IOP elevation rat models 22,23

Fortin JP, Triche TJ, Hansen KD

reported an increase in the protein-bound form of glutathione in human blood after oral administration, while glutathione in the deproteinized fraction did not change [12]

Chemotherapeutic agents can be encapsulated within hydrogel matrices to sustain high intratumoral concentrations while limiting systemic exposure, addressing one of the fundamental shortcomings of conventional chemotherapy [155]

Non-enzymatic glutathionylation occur mostly during oxidative stress when GSH/GSSG is ~1 and levels of ROS are high

Growth and Des