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The role of oxidative stress in the activation and function of immune cells is also critical in autoimmune diseases [133]

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Research suggests that after injury to skeletal muscle, the IGF-1Eb mRNA splice variant is up-regulated initially, followed by up-regulation of the IGF-1Ea splice variant at later time points

Insulin-like growth factor-binding protein (IGFBP-3) predisposes breast cancer cells to programmed cell death in a non-IGF-dependent manner