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It can also decrease inflammation by reducing levels of other cytokines like interleukin (IL) and tumor necrosis factor-alpha (TNF-alpha)

Other proposed contributors discussed in the literature include modulation of the dopaminergic and serotonergic systems, growth hormone receptor expression in fibroblasts, and interaction with the nitric oxide system at the level of vasomotor regulation (Sikiric et al., 2018)

Solutions must be designed to be compatible with existing interface standards and open architecture(s) across multiple domains