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Namely, the irreversible monoamine oxidase (MAO B) inhibition (i.e., pargyline) and subsequent serotonin substrate (L-tryptophan as a serotonin precursor) induced fore paw treading, hind limbs abduction, wet dog shake, and hypothermia followed by hyperthermia in rats, which commonly occur in serotonin syndrome [66]

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Excessive foam indicates the water hit the powder directly instead of running down the vial wall

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