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Ghoneum M, Agrawal S

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The overall fold of human TrxR1 resembles other homodimeric pyridine nucleotide disulphide oxidoreductases such as rat TrxR1 (ref

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Breakthrough studies reveal that fucoxanthin (FX) establishes an AMPK/Nrf2/TLR4 tripartite regulatory network, achieving molecular-level metabolic modulation through enhanced AMPK-Thr172 phosphorylation, reduced SREBP-1c nuclear translocation, and downregulated FAS and ACC expression