2011, doi: 10.1016/j.cell.2011.02.013
As the main transcription factor of Th17 cell, RORt collaborates with other transcription factors, such as ROR, IRF4, and Runx1, to synergistically stimulate Th17 cell growth and IL-17 release ( Foxp3 interacts with several transcription factors, such as STAT5, NFAT, and BACH2, to influence the Treg cells' development, stability, and epigenetic modifications
Jia Y, Zhang Q, Weng C, Ramage CL, Nishida Y, Chao M, Maute RL, Herbrich S, Zhang W, Andreeff M , Daver N, Konopleva M
No significant differences were found between the intervention and control groups at the end of study in serum myeloperoxidase, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, total oxidant capacity, or total oxidant capacity (Table 4)
No published pharmacokinetic data
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