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In addition, according to the literature, we know that resveratrol can activate microglia, promote the M2 polarization of microglia and reduce neuroinflammation [37, 38]

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456 In the spinal cord, the influx of neuropathic signals to the dorsal horn leads to central sensitization, characterized by increased spontaneous neuronal activity, lowered activation thresholds for peripheral stimuli, heightened responses to sub-threshold stimuli, and expansion of receptive fields

But these changes occur gradually, meaning that its unlikely for a flare of symptoms to be caused by a surge in antibodies associated with Hashimotos