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Additionally, Karin et al.'s research indicates that the activation of T-cells hinges on glycolysis that perpetually generates lactate, and the accumulation of lactate in cells throws T-cells' metabolism into disorder and retards their activation [99]

318 In addition, the appropriate timing of drug administration is critical, particularly in patient stratification and drug delivery

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We've seen this play out in various regenerative contexts within our Performance & Recovery Research