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Once lodged, the venom is pushed into the wound using a separate piston mechanism (Lee et al., 2020)

This resolves as models stabilize

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The highest binding affinity for GPx4 with a docking score of 7.6kcal/mol and greater ligand exposure was exhibited by Lapatinib, which bonded with the enzyme at ASP165 and TYR169 residues

The three groups (healthy controls, pre-RA and RA patients) were balanced for age, sex and body mass index within their respective cohorts

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