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Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism ( MITOCHONDRIAL ROS GENERATION AND DEFENSE Reactive oxygen species can be generated in several intracellular sites, including cytosol, peroxisomes, plasma membrane, and ER

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Hatsugai M, Kurokawa MS, Kouro T et al (2009) Protein profiles of peripheral blood mononuclear cells are useful for differential diagnosis of ulcerative colitis and Crohns disease