Regulation of GSK3/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer
incomplete toxicological characterisation
doi: 10.1016/j.ymgme.2016.09.001 155
Ions flowing, neurons firing: Neurons fire by building up an action potential by moving ions (e.g., calcium, potassium, chlorine) into or out of the cell, causing a change in the polarization
Harmful metabolites cross the gut intestinal barrier, activate immune cells, including dendritic cells, macrophages, and neutrophils, and produce pro-inflammatory cytokines, such as IL-1 and TNF-, leading to inflammatory reactions
A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells