10.1186/s13098-020-0518-7 Diabetol
Balan, H., Popescu, E
The data are presented as mean SD from three independent experiments
Hot water extraction involves boiling the materials in water to extract polymers with antioxidant compounds, which is low-cost, simple, and safe but yields low amounts (1040%) and may damage antioxidant polymers due to high temperatures (Mohanta et al., 2023)
It is not for retail sale or home use without direct medical supervision
A role of oxidative stress in GO is supported by a number of basic studies suggesting that ROS promote the proliferation of OFs and the release of GAGs, the synthesis and secretion of cytokines, and the expression of other factors involved in the pathogenesis of GO, namely heat shock protein 72 (HSP-72), HLA-DR and ICAM-1 ( Figure 1 In this context, a number of studies, performed both in vitro and in vivo , investigated the effects of antioxidant agents in GO, including selenium, pentoxifylline, quercetin, enalapril, vitamin C, N-acetyl-L-cysteine and melatonin ( Oxidative Stress and Proliferation of Orbital Fibroblasts Burch et al
