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The calculated binding affinities for compound 110 against glutathione S-transferase (PDB ID: 1gtb) were 29.7, 29.3, 31.0, 31.4, 31.8, 33.5, 30.5, 34.3, 34.3, and 31.4 kJ mol 1 , respectively

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2e (iii)), and the particularly pronounced bulbous phenotype reminiscent of spore-containing filaments (Fig