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Some MCD biological activity takes different routes and might be an excellent example of the structure-function link (Figure 2)

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The core mechanism lies in the counteraction between the reduction system represented by GPX4/GSH and the oxidation system represented by Fe/ACSL4/PLOOH 49

Similar results were observed when tumours were implanted into the flanks of mice, a result that suggests that this phenotype is not specific to the mammary gland environment (Extended Data Fig

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