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10.1038/onc.2017.216 Oncogene 139 VazF

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This is because there are a finite number of stem cells in the body, and if damage occurs this early into the step-process, we lose the ability to produce healthy melanocytes, and thereby melanin (hair pigment)

43 The relevance of this pathway for tumorigenesis is demonstrated by the fact that humans with the Laron syndrome, a recessively inherited defect in the growth hormone receptor, display extremely low IGF-1 and reduced insulin concentrations and usually do not develop cancer despite high prevalence of obesity and dyslipidemia

Thus, the combination of MNMs and macrophage research holds promise for future tumor treatment