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Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury

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Members of the oligopeptide transporters (OPTs) might be responsible for transport of glutathione and its derivates across the plasma membrane, however the opt1-3 and opt6 mutants tested in our study did not exhibit any phenotype difference to WT when exposed to AITC

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Supplementation with 300-600 mg/day has been shown to increase intracellular glutathione levels by 30-70% in cell culture and animal studies, with more modest increases in human trials (Suh et al., Proc Natl Acad Sci, 2004) [25]