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& Lischer, H

Rossella Cannarella, lead investigator on the study, this dual action means tirzepatide could become a first-line treatment option for men whose testosterone issues are rooted in metabolic health, rather than structural damage to the testes

The recent discovery of pharmacological ABHD5 ligands that disrupt the interaction between ABHD5 and PLIN1 (48) demonstrate that the dissociation of ABHD5 is sufficient to stimulate adipocyte lipolysis and that these protein interactions can be targeted pharmacologically (34, 48, 49)

doi: 10.1016/S0197-0186(96)00025-3

J Pharm Bioallied Sci