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To assist in readability, analysis looking at other relationships between the variable studied are presented in the Supplementary results
However, these detoxification mechanisms could also provide protection from oxidative membrane damage via immune assault, internal toxic compounds of helminth metabolism, as well as xenobiotics, such as anthelmintics (van Rossum et al ., Reference van Rossum, Jefferies, Rijsewijk, LaCourse, Teesdale-Spittle, Barrett, Tait and Brophy2004
Hemolytic toxicity restricts the available administration routes, while significant variations in activity among individual saponins hinder standardized implementation
However, a recent human clinical trial has provided new insights into its potential benefits for chronic pain management