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Mild deficiency: Patients with mild B12 deficiency might only need a small dose

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57 SeiwerthS.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)

Observed Side Effects (From Clinical Trials) In the Lancet 2021 Phase 2 trial (n=706), at the highest 4.5 mg/week dose, 88% of participants reported at least one side effect and 63% reported a GI-specific event

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