They include UGT1A1, UGT1A8, and UGT1A9 exhibiting both competitive and non-competitive inhibition, resulting in the production of quercetin conjugates like glucuronides, which are vital in influencing the bioavailability of the compound (Zhang et al., 2021)
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Therefore, selenium deficiency is associated with thyroid dysfunction and increased risk of thyroid autoimmunity and nodules [65], a condition further aggravated by the fact that concurrent iodine and selenium deficiency is rather common [66, 67]
Excessive ROS are produced in physiological functions such as mitochondrial function and phagocytic activity
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