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(PubMed) Stabler SP

Mol Carcinog 22, 22934

Cagrilintide's primary site of action for appetite regulation is the area postrema (AP), a sensory circumventricular organ in the hindbrain that lacks a complete blood-brain barrier

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Immediate effect (day 3): Whereas the controls exhibited an increasing disappearance of arcade vessels, particularly at the dorsal side of the colon (Figures 9, 13 and 14), after BPC 157 bath treatment the arcade vessels vigorously reappeared together with interconnected collaterals between arcades, in particular, quickly rescuing blood flow (a finding especially seen at the dorsal side of the colon) (Figures 18, 21 and 22)