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It was shown that in apolipoprotein E-deficient mice fed a high-fat diet, which is a widely used murine model for atherosclerosis, supplementation of CoQ 10 resulted in a variable increase of the total aortic content of CoQ and in reduced aortic LOOH accumulation as well as in a smaller area of atherosclerotic lesions in the aorta (317, 323)

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Obese mice and rats treated with AOD9604 showed significant decreases in adipose tissue depot weights, reductions in adipocyte size observed histologically, and improvements in body composition measured by DEXA scanning or MRI

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2010 Cadmium activates Arabidopsis MPK3 and MPK6 via accumulation of reactive oxygen species