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The peroxisome proliferator-activated receptor gamma (PPAR) pathway-which regulates macrophage polarizationis suppressed, further favoring M1 polarization (95, 96)

Neurogenesis in the adult vertebrate and human brain was first identified 25 years ago [47]

Nanotechnology offers a promising approach to overcome these limitations by enhancing drug delivery, reducing recurrence, and addressing antimicrobial resistance (206)

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Hydrogen peroxide increases the activities of soxRS regulon enzymes and the levels of oxidized proteins and lipids in Escherichia coli

Aberrant immune responses promote vascular inflammation, leading to endothelial dysfunction, vascular remodeling, and increased peripheral vascular resistance, which eventually drive blood pressure elevation (235, 236)