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Curr Pharm Design 10:879891 Chen Z, Zhang Y, Ma L, Ni Y, Zhao H (2016) Nrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and death

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Hence, changes in intra-portal insulin levels need to be taken into consideration to correctly interpret the alterations in the GH/IGF-I axis in healthy and disease states as this helps the clinician in formulating the decision-making process of when and how to perform appropriate diagnostic work-up and whether to offer treatment to improve any accompanying metabolic consequences