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16 Although these authors found 100% specificities with sensitivities of 80 and 82% for arthrography and MRI (respectively), arthroscopic visualization of a TFCC tear continues to be the gold standard for definitive diagnosis

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These diabetes-specific results mirror the pattern seen with CagriSema in REDEFINE 2, though direct comparison requires caution because the trial populations and designs differed

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and smooth DOIs allow controlled undercoverage in exchange for over-inclusion in set covering models, including the CVRP (Haghani et al

Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work