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The half-life and solubility of growth factors, the proper carrier, and the presence of inhibitors need to be taken into consideration when growth factors are used in regenerative strategies [84]

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Conclusions Ultimately, the current maintenance dose of 1,000 mcg B12 every 3 months may confer long term harm, therefore it seems that once B12 levels are stabilised well within acceptable range, then the standard B12 intervention of 1000 mcg should be administered annually, and monitored with pre-injection annual testing of levels

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While it's known for its powerful fat-releasing (lipolytic) effects, it also influences muscle growth, blood sugar levels, and cellular growth (the IGF-1 pathway)