Malhotra A et al., SURMOUNT-OSA, NEJM 2024 (NEJMoa2404881, PMID 38912654) : tirzepatide and obstructive sleep apnea, AHI -25,3 to 52 weeks
KPV and Longevity One of the most exciting areas of peptide medicine is targeting chronic inflammation, often called inflammaging. Inflammaging is associated with: Biological aging Cardiovascular disease Cognitive decline Sarcopenia Metabolic disease By helping regulate inflammatory pathways, KPV may eventually become part of future longevity-focused therapeutic strategies
+ Nobiletin was shown to increase hepatic fatty acid oxidation, decrease fatty acid synthesis and decrease inflammatory gene transcription factors
Data indicates that investigators using 5-Amino-1MQ in the same research program as Tirzepatide or Semaglutide often do so to compare signalling breadth, tissue selectivity, or pathway overlap
~ AlphaMD So you've been prescribed testosterone replacement therapy , or you're thinking about it, and naturally you do what anyone in 2025 doesyou head to Reddit, join a Facebook group, or start lurking in a Discord server dedicated to TRT
Vd= volume of distribution
