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Pycnogenol has been shown to have four main effects being its antioxidative effects (914), its anti-inflammatory action (1518), its positive impact on blood circulation (9, 1924) and its reinforcing effects on the extracellular matrix (25, 26) (Figure 1)

Povlsen and Tegnell tracked the incidence of pillar pain after open CTR during 3 years

5.4.3 Anti-fungal activity Fungal infections harm over a billion people globally and cause about 1.5 million deaths each year (Silva et al., 2019)

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