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At the December 2024 PCAC meeting, the committee evaluated CJC 1295 in multiple forms including the DAC variant
The authors show that the drastic growth arrest of the sir1 mutant is partially rescued when glutathione deficiency is introduced via the cad2 mutation, which decreases glutathione levels to 30% to 40% of wild-type levels (Cobbett et al., 1998), or pharmacologically through treatment with the GCL inhibitor buthionine sulfoximine
and solicit feedback from LTCHs for future enhancements to the methods