Moreover, zebrafish share conserved physiological and biochemical pathways with humans, enhancing their relevance for studying human diseases and antioxidant mechanisms
doi: 10.1172/jci36470, 20 BrodackiB.StaszewskiJ.ToczyowskaB.KozowskaE.DrelaN.ChalimoniukM.et al
C (101 MHz, CDCl 3 ): 170.176 (C 2), 135.18 (d, J = 2.8 Hz, CH 6), 133.57 (d, J = 9.8 Hz, CH 12), 130.59 (d, J = 12.5 Hz, CH 12), 118.10 (d, J = 85.9 Hz, C 6), 38.58 (CH 2 2), 36.56 (CH 2 2), 27.97 (CH 2 2), 27.27 (d, J = 16.5 Hz, CH 2 2), 22.50 (d, J = 50.8 Hz, CH 2 2), 21.83 (d, J = 4.2 Hz, CH 2 2)
[DOI] [PubMed] [Google Scholar] 30.Thannickal VJ, Fanburg BL
DAPLE protein inhibits nucleotide exchange on G s and G q via the same motif that activates G i
H (400 MHz, MeOD): 4.62 (1 H, dd, J = 9.1, 4.9 Hz, H-4), 4.06 (1H, t, J = 6.4 Hz, H-1), 3.89 (1 H, d, J = 17.8 Hz, H-6 A or B ), 3.85 (1 H, d, J = 17.8 Hz, H-6 A or B ), 3.483.36 (2 H, m, PCH 2 ), 3.26 (1 H, d, J = 14.8 Hz, H-7 A or B ), 3.20 (1 H, d, J = 14.8 Hz, H-7 A or B ), 3.19 (2 H, d, J = 6.4 Hz, H-8), 3.10 (1 H, dd, J 14.0, 4.9 Hz, H-5 A or B ), 2.85 (1 H, dd, J = 14.0, 9.1 Hz, H-5 A or B ), 2.59 (2 H, t, J = 7.1 Hz, H-3), 2.332.22 (1 H, m, H-2 A or B ), 2.222.12 (1 H, m, H-2 A or B ),1.761.65 (2 H, m, CH 2 ), 1.651.51 (4 H, m, CH 2 )
