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Side effects are rare but may include mild pain at the injection site or slight nausea

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However, there is no evidence that B12 injections confer any greater benefit than does a good quality B vitamin complex, even in cases of B vitamin deficiency

In the United States, bacteriostatic water for injection is classified as a prescription-only product

therefore, it does not appear to trigger diabetes development or induce glucose intolerance in test models, though further studies are necessary to explore this aspect

Table 2 Immune alterations present in ME/CFS and changes evident in B cells, T cells, and NK cells (99, 253255, 278, 445482)