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K., Kokare, D

developed a biomimetic nanomotor capable of traversing the BBB and penetrating deeper ischemic and hypoxic brain regions

This raises important questions about how long treatment should continue

In numerous animal models, sulforaphane (often administered ip, iv, or sc, rather than po) was shown to exert protective effects on many tissues and organs by activating the Nrf2/ARE-dependent pathway (12)

However, a notable side effect was observed: MT-II-treated normal C57BL/6J mice exhibited significant weight loss, with their average weight decreasing from a baseline of 30.9 1.4 grams to 26.5 1.7 grams after the 14-day treatment course, a change not seen in vehicle-treated controls

Ashwood, editors