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The Future of MOTS-C Research: What Is Coming The MOTS-c field is advancing rapidly, with several threads of research likely to reshape clinical dosing recommendations within the next five years

To further implement GLP-1RA-centric combination therapy, we need to consider some evidence gaps (Table 4)

The direction of effect is consistent

Older adults may respond more slowly to both compounds but often appreciate the benefits of Sermorelin more acutely, as their baseline growth hormone levels are typically lower

Both approaches deliver distinct advantages based on user needs