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Effective treatment of luminal disease, maintenance of hydration, mobilization, treatment of vitamin deficiencies (folate, vitamins B12 and B6), and prophylaxis for high-risk patients should be instituted

Higher doses of berberine may be needed in order to reduce Lp(a)[ref][ref]

Glutathione is the master antioxidant produced by the body and needed in larger amounts as we age, when exposed to toxins and oxidative compounds

Adapter sequences were removed with cutadapt (v2.9) (Schmieder and Edwards, 2011) was used to filter and trim the end of the reads by quality

Initially, the data were assessed for normality and homoscedasticity

Above all, this work reflects the dedication of investigators, site teams, and patientswhose trust, collaboration, and commitment made this study possible