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Apigenin reverses behavioural impairments and cognitive decline in kindled mice via CREB-BDNF upregulation in the hippocampus

The food optimization strategies that apply to GLP-1 medications generally are a starting point, but the higher energy expenditure with retatrutide warrants adjustment

While this rapid evolution toward multi-agonist strategies and oral formulations promises enhanced efficacy, tolerability, and adherence, generating robust long-term safety and efficacy evidence remains imperative

Selective elimination of mitochondria by mitophagy, in conjunction with mitochondrial biogenesis, regulates mitochondrial function that is required to meet metabolic demand or stress response

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