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RCT conducted in patients with T2D showed that high doses of tirzepatide represent the most efficacious incretin-based anti-diabetes drug in terms of BW reduction 33 , sustaining the development of the SURMOUNT program to explore its efficacy and safety in the management of obesity 9

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The total amount of anthocyanins in the serum was directly proportional to increased oxygen radical absorbance capacity (ORAC) (Mazza et al