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Folate, particularly methylfolate, can worsen this by further increasing SERT and dopamine transporter (DERT) activity, potentially leading to increased anxiety, OCD-like symptoms, emotional instability, and cognitive rigidity

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Consult Healthcare Providers: Seek medical guidance before starting BPC-157, especially for individuals with pre-existing conditions or taking concurrent medications

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But the mechanistic rationale is strong, the safety profile appears favorable, and the early observational data aligns with what the biochemistry predicts