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However, therapies targeting TNF or IL-1 have shown only moderate effectiveness in OA, suggesting the involvement of additional inflammatory pathways

The two therapies run on parallel tracks

TMX group) inhibited cleaved caspase-3 (36%) and GFAP (13%) expression in the brain (Fig

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Nutrients frequently studied in connection with neurotrophic signaling include omega-3 DHA, magnesium, vitamin D, curcumin, flavonoids from cocoa or green tea, and B-vitamins involved in methylation and neurotransmitter production, which help support neuronal communication and brain metabolic health