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doi: 10.1007/bf00304630 104

Free Radic Biol Med (2014) 71:28190.10.1016/j.freeradbiomed.2014.03.019 18 AbbasKBabicNPeyrotF

Biophysical characterization of aptamer-target interactions

Within the models, the dynamics of O 2 are not explicitly specified but rather, assumed to be constant as k Q 2, due to a separation of scales

They bind to specific receptors on cell surfaces, triggering downstream signaling cascades that regulate everything from growth and metabolism to immune responses and neurological function

Activation of TLRs is a cornerstone of innate immunity, triggering key defense responses against invading pathogens (260)